Chakravarthy Lab – Team
Dr. Krishnan Chakravarthy – Laboratory Head
(Assistant Clinical Professor of Anesthesiology and Pain Medicine – UC San Diego Health Sciences, VA San Diego Health Care, San Diego, CA, USA)
Dr. Chakravarthy’s current and future research interests follow three distinct trajectories. One aspect of his work involves the use of molecular, cellular, and whole animal strategies to elucidate the physiology and pathophysiology of chronic pain in different pain systems. His laboratory utilizes a combination of in vitro and in vivo techniques to study the mechanisms behind neuropathic pain, complex regional pain syndrome, and diabetic neuropathy.
The second area of focus investigates of the effects of general and local anesthetics in modulating host immunity to various viral and bacterial infections. Chakravarthy’s emphasis as a clinician scientist is to translate findings in basic science to effective therapies, which may be applied in clinical trials for eventual use in patients. To this end, the third area of focus is nanomedicine (the application of nanotechnology to medicine) with an aim to develop novel diagnostic and therapeutic platforms to efficaciously address various chronic pain states.
Dr. Chakravarthy completed his sub-specialty fellowship training in pain management at the Massachusetts General Hospital/Harvard Medical School, and residency training in anesthesiology at The Johns Hopkins Hospital in Baltimore, MD. He interned in general medicine at Griffin Hospital (Yale Affiliate) in Derby, Connecticut, and earned his M.D. and Ph.D. degrees at the Jacobs School of Medicine and Biomedical Sciences in Buffalo, NY. His notable awards include being nominated for the American Society of Regional Anesthesiology and Pain Medicine Resident/Fellow of the Year Award, Griffin Hospital (Yale Affiliated) Intern Physician of the Year Award Recipient, Buffalo Business First “Rising Star”, University at Buffalo Henry Panasci Technology Entrepreneurship Competition Award Winner, and recipient of the National Institute of Health Ruth L. Kirschstein National Research Service Award.
Dr. Kelly Bruno, MD
(Pain Medicine Research Fellow – UC San Diego Health Sciences, VA San Diego Health Care, San Diego, CA, USA)
Dr. Bruno completed medical school and residency training in Anesthesiology at the University of North Carolina after receiving her undergraduate degree from Duke University. She is currently pursuing dual-fellowship training in pain medicine and mental health/chronic pain research at UC San Diego.
Her research interest is understanding mechanisms leading to chronic post-amputation pain through basic and translational research.
Outside of medicine, Kelly is an avid ultrarunner, triathlete and co-owner of an internationally positioned health and fitness business. She is the world record holder for female amputees at the Ironman World Championships and has podiumed at multiple ITU World Triathlon Championships.
Kelly was also a contestant on the American reality TV show, Survivor Nicaragua, which aired in 2010.
Dr. Joel Martin, MD
(Neurosurgeon – Department of UCSD Neurological Surgery.)
Dr. Martin works with the Chakravarthy Laboratory on advancing our neuromodulation program for pain and movement applications. His goal as a physician-scientist is to combine neural prosthetics research and practice.
He is interested in the clinical application and surgical placement of neural prosthetics, and being one step closer to the dream of restoring neurological function to disabled patients.